NR1I3 MaxPab rabbit polyclonal antibody (D01)
产品名称： NR1I3 MaxPab rabbit polyclonal antibody (D01)
英文名称： NR1I3 MaxPab rabbit polyclonal antibody (D01)
产品编号： H00009970-D01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against a full-length human NR1I3 protein.
- Immunogen:
- NR1I3 (NP_001070948.1, 1 a.a. ~ 352 a.a) full-length human protein.
- Sequence:
- MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS
- Host:
- Rabbit
- Reactivity:
- Human
- Storage Buffer:
- No additive
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of NR1I3 expression in transfected 293T cell line (H00009970-T02) by NR1I3 MaxPab polyclonal antibody.
Lane 1: NR1I3 transfected lysate(39.9 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Immunoprecipitation
- Immunoprecipitation of NR1I3 transfected lysate using anti-NR1I3 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with NR1I3 purified MaxPab mouse polyclonal antibody (B01P) (H00009970-B01P).
- Protocol Download
- Entrez GeneID:
- 9970
- GeneBank Accession#:
- BC069626.1
- Protein Accession#:
- NP_001070948.1
- Gene Name:
- NR1I3
- Gene Alias:
- CAR,CAR1,MB67,MGC150433,MGC97144,MGC97209
- Gene Description:
- nuclear receptor subfamily 1, group I, member 3
- Omim ID:
- 603881
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety of foreign compounds, steroid hormones, and prescription drugs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000032245,OTTHUMP00000032246,constitutive activator of retinoid response,constitutive active receptor,constitutive androstane receptor,orphan nuclear hormone receptor
- Related Disease