Monoclonal Antibody against Apolipoprotein-D-抗体-抗体-生物在线
翌圣生物科技(上海)股份有限公司
Monoclonal Antibody against Apolipoprotein-D

Monoclonal Antibody against Apolipoprotein-D

商家询价

产品名称: Monoclonal Antibody against Apolipoprotein-D

英文名称: Monoclonal Antibody against Apolipoprotein-D

产品编号: SIG-39780

产品价格: null

产品产地: USA

品牌商标: COVANCE

更新时间: 2024-12-10T13:18:22

使用范围:

翌圣生物科技(上海)股份有限公司
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Description Apo-D (GCDFP-24) Monoclonal Antibody (SIGNET) - SIGNET ANTIBODIES Monoclonal Antibody against Apolipoprotein-D (ApoD)
(Formerly Signet Catalog Nos: 9780-02, 9780-05, 9780-10)
Intended Use **Research Use Only (RUO)**

This product is sold for laboratory research use only, not for human or in-vivo use.
Clone 8CD6
Form Tissue Culture Supernatant (in PBS; no preservatives or carrier proteins)
Host Mouse
IsoType IgG1
[Ab] Apo-D (GCDFP-24) Monoclonal Antibody (SIGNET) - SIGNET ANTIBODIES 1 mg/mL
Specificity Apo-D (GCDFP-24) Monoclonal Antibody (SIGNET) - SIGNET ANTIBODIES The anti-APO-D antibody, clone 8CD6, recognizes Apolipoprotein-D, a 24 kDa progesterone binding glycoprotein.

This antibody was generated against APO-D, a progesterone binding glycoprotein of 24,000 dalton monomer molecular size.
Uses Apo-D (GCDFP-24) Monoclonal Antibody (SIGNET) - SIGNET ANTIBODIES This antibody is effective in immunoblotting, immunohistochemistry (IHC) and ELISA.
Suggested Working Dilution Apo-D (GCDFP-24) Monoclonal Antibody (SIGNET) - SIGNET ANTIBODIES The optimal working dilution should be determined for each specific assay condition.
  • Western: 1:1,000-1:10,000
  • IHC: 1:200 for biotin based detection systems such as USA Ultrastreptavidin Detection (SIG-32250)
    Tissue Sections: Formalin-fixed, paraffin-embedded tissues
    Pretreatment: For optimal staining, the sections should be pretreated with an antigen unmasking solution such as Retrieve-All 1 (SIG-31910) or Sodium Citrate (SIG-31932)
    Incubation: 20-60 min at room temperature
Storage Apo-D (GCDFP-24) Monoclonal Antibody (SIGNET) - SIGNET ANTIBODIES Store at -20°C or below. Upon initial thawing, apportion into working aliquots and store at -20°C or below. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody. Do not store in frost-free freezers.
References Thomas EA, et al. Increased CNS levels of apolipoprotein D in schizophrenic and bipolar subjects: Implications for the pathophysiology of psychiatric disorders. Proc Natl Acad Sci 98(7):4066-4071, 2001.

Kolodny EH. Niemann-Pick disease. Curr Opin Hematol 7(1):48-52, 2000.

Kalman J, et al. Apolipoprotein D in the aging brain and in Alzheimer’s dementia. Neurol Res 22(4):330-6, 2000. Franz G, et al. Increased expression of apolipoprotein D following experimental traumatic brain injury. J Neurochem 73(4):1615-25, (1999).

Montpied P, et al. Hippocampal alterations of apolipoprotein E and D mRNA in vivo and in vitro following kainate excitoxicity. Epilepsy Res 35(2):135-46, 1999.

Navarro A, et al. Pattern of apolipoprotein D immunoreactivity in human brain. Neurosci Letts 254(1):17-20, 1998.

Suresh S, et al. Cellular cholesterol storage in the Niemann-Pick disease type C mouse is associated with increased expression and defective processing of apolipoprotein D. J Neurochem 70(1):242-51, 1998.

Terrisse L, et al. Increased levels of apolipoprotein D in cerebrospinal fluid and hippocampus of Alzheimer’s patients. J Neurochem 71(4):1643-50, 1998.

Ong, WY, et al. Differential expression of apolipoprotein D and aApolipoprotein E in the kainic acid-lesioned rat hippocampus. Neurosci 79:359-367, 1997.

Zeng C, et al. A human axillary odorant is carried by apoprotein D. Proc Natl Acad Sci USA, 93:6626-6630, 1996.

Aspinall JO, et al. Differential expression of apoprotein-D and prostate specific antigen in benign and malignant prostate tissues. J Urol 154:622-628, 1995.
Warranty/Conditions Apo-D (GCDFP-24) Monoclonal Antibody (SIGNET) - SIGNET ANTIBODIES Covance products may not be resold or modified for resale without prior written approval.
Rev. Date Apo-D (GCDFP-24) Monoclonal Antibody (SIGNET) - SIGNET ANTIBODIES 4/18/2009