FITC标记的肿瘤/睾丸抗原2.3抗体-抗体-抗体-生物在线
上海沪震实业有限公司
FITC标记的肿瘤/睾丸抗原2.3抗体

FITC标记的肿瘤/睾丸抗原2.3抗体

商家询价

产品名称: FITC标记的肿瘤/睾丸抗原2.3抗体

英文名称: Anti-BAGE3/FITC

产品编号: HZ-9115R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: IF=1:50-200

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 Rabbit Anti-BAGE3/FITC Conjugated antibody

FITC标记的肿瘤/睾丸抗原2.3抗体

 

产品编号 bs-9115R-FITC
英文名称 Anti-BAGE3/FITC
中文名称 FITC标记的肿瘤/睾丸抗原2.3抗体
别    名 B melanoma antigen family member 3; B melanoma antigen 3; BAGE3; BAGE3_HUMAN; Cancer/testis antigen 2.3; Cancer/testis antigen family 2 member 3; CT2.3.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 10kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human BAGE3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Unknown. Candidate gene encoding tumor antigens. Members of the BAGE gene family encode antigens that are recognized by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements.Generally, BAGE proteins are silent in all normal tissues with the exception of testis. BAGE2 and BAGE 3 (B melanoma antigen 2 and 3, respectively), also known as Cancer/testis antigen 2.2 and 2.3 (respectively), are 109 amino acid secreted proteins that are expressed in 22% of melanomas, lung and bladder carcinomas, and are also expressed in normal testis tissue. Like the genes encoding MAGE proteins, BAGE genes are most likely silenced by DNA methylation and/or chromatin compaction in normal tissues other than testis.

Function:
Unknown. Candidate gene encoding tumor antigens. 

Subcellular Location:
Secreted

Tissue Specificity:
Not expressed in normal tissues except in testis. Expressed in melanoma, bladder and lung carcinomas.

Similarity:
Belongs to the BAGE family. 

Database links:
UniProtKB/Swiss-Prot: Q86Y29.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   

未知的。编码肿瘤抗原的候选基因。BAGE基因家族的成员编码由细胞毒性T淋巴细胞识别的抗原,也称为CT(癌/睾丸)抗原。通过MLL3基因的等位基因混洗,祖先的BEG基因通过近端着丝粒交换和/或左右着丝粒运动而扩展。一般而言,除了睾丸以外,所有的正常组织中的BEP蛋白都是沉默的。BAGE2和BAGE 3(B黑色素瘤抗原2和3),也称为癌/睾丸抗原2.2和2.3(分别)是109个氨基酸分泌蛋白,在22%个黑色素瘤、肺和膀胱癌中表达,并且在正常睾丸组织中也表达。与编码MAGE蛋白的基因一样,在睾丸以外的正常组织中,BEG基因最有可能被DNA甲基化和/或染色质压实所沉默。