SHMT1 (Human) Recombinant Protein (P01)
产品名称： SHMT1 (Human) Recombinant Protein (P01)
英文名称： SHMT1 (Human) Recombinant Protein (P01)
产品编号： H00006470-P01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human SHMT1 full-length ORF ( NP_004160.3, 1 a.a. - 483 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPGLPDF
- Theoretical MW (kDa):
- 79.5
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 6470
- GeneBank Accession#:
- NM_004169.3
- Protein Accession#:
- NP_004160.3
- Gene Name:
- SHMT1
- Gene Alias:
- CSHMT,MGC15229,MGC24556,SHMT
- Gene Description:
- serine hydroxymethyltransferase 1 (soluble)
- Omim ID:
- 182144
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq
- Other Designations:
- 14 kDa protein,cytoplasmic serine hydroxymethyltransferase
- Related Disease
- Adenocarcinoma
- Adenoma
- Aortic Aneurysm, Abdominal
- Arthritis, Rheumatoid
- Atherosclerosis
- Autistic Disorder
- Bone Neoplasms
- Brain Ischemia
- Breast cancer
- Breast Neoplasms
- Carcinoma, Squamous Cell
- Cardiovascular Diseases
- Cleft Lip
- Cleft Palate
- Colorectal Neoplasms
- Disease Models, Animal
- Ductus Arteriosus, Patent
- Epilepsy
- Epilepsy