FITC标记的9号染色体开放阅读框59抗体
产品名称： FITC标记的9号染色体开放阅读框59抗体
英文名称： Anti-C9orf59/FITC
产品编号： HZ-9656R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-C9orf59/FITC Conjugated antibody
FITC标记的9号染色体开放阅读框59抗体
| 产品编号 | bs-9656R-FITC |
| 英文名称 | Anti-C9orf59/FITC |
| 中文名称 | FITC标记的9号染色体开放阅读框59抗体 |
| 别 名 | C9orf59; Chromosome 9 open reading frame 59; Family with sequence similarity 78, member A; FLJ00024; Hypothetical protein LOC286336;FAM78A. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 神经生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Rabbit, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 32kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FAM78A/C9orf59 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Chromosome 9 consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias. The FAM78A gene product has been provisionally designated FAM78A pending further characterization. Similarity: Belongs to the FAM78 family. Database links: Entrez Gene: 286336 Human Entrez Gene: 241303 Mouse Entrez Gene: 499776 Rat SwissProt: Q5JUQ0 Human SwissProt: Q8C552 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
9号染色体由约1亿4500万个碱基和4%个人类基因组组成，编码近900个基因。认为在性别决定中起作用的是，9P末端的缺失可导致男性与女性性别逆转的发展，一个具有男性X、Y基因型的女性的表型。遗传性出血性毛细血管扩张症，其特征是由有害的血管缺陷，与编码EngGLN蛋白的染色体9基因有关。家族性失代偿也通过基因IKBKAP与9号染色体相关。值得注意的是，9号染色体包含最大的干扰素家族基因簇。染色体9与易位的22号染色体相关，导致BCR-ABL融合蛋白在白血病中的异常生成。FAM78A基因产物已暂时指定为FAM78A，有待进一步鉴定。