CRLS1-Specific 抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
CRLS1-Specific 抗体

CRLS1-Specific 抗体

商家询价

产品名称： CRLS1-Specific 抗体

英文名称： CRLS1-Specific Antibody

产品编号： XY 14845-1-

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 CRLS1-SPECIFIC 抗体

Applications
In-house applications ELISA, IHC     Application not tested? Please see our Guarantee.
Published applications WB Publications 2 citations –view here
Species specificity Human,Mouse,Rat; other species not tested.
Published Species Human, rat
Images
Prev1NextView more validation data
  • 14845-1-AP;human liver cancerImmunohistochemical of paraffin-embedded human liver cancer using 14845-1-AP(CRLS1-Specific antibody) at dilution of 1:50 (under 40x lens)
  • 14845-1-AP;human liver cancerImmunohistochemical of paraffin-embedded human liver cancer using 14845-1-AP(CRLS1-Specific antibody) at dilution of 1:50 (under 10x lens)
Positive IHC detected in Human liver cancer tissue
Recommended dilution IHC : 1:20-1:200
CRLS1-SPECIFIC 抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen Peptide Full name Cardiolipin synthase 1
Calculated molecular
weight		 33 kDa Observed molecular 
weight		 32 kDa
GenBank accession 
number		 NM_019095 Gene ID (NCBI) 54675
Gene symbol CRLS1 Synonyms C20orf155, Cardiolipin synthase, cardiolipin synthase 1, CLS, CLS1, CRLS1, dJ967N21.6, GCD10, Protein GCD10 homolog
BackgroundCRLS1-SPECIFIC 抗体

Cardiolipin (CL) is a mitochondrial specific double negatively charged phospholipid which is intricately involved in regulating bioenergetic efficiency. In eukaryotes, CL is synthesized by cardiolipin synthase (CRLS1 or CLS1) which catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form CL and glycerol. Recently it has been reported that transgenic expression of CRLS1 accelerates cardiolipin remodeling, improves mitochondrial function, modulates mitochondrial signaling, and attenuates mitochondrial dysfunction during diabetes, thereby identifying CRLS1 as a novel therapeutic target to attenuate mitochondrial dysfunction in diabetic myocardium.CRLS1-SPECIFIC 抗体

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