SUPT6H抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
SUPT6H抗体

SUPT6H抗体

商家询价

产品名称： SUPT6H抗体

英文名称： SUPT6HAntibody

产品编号： XY23073-1-

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 SUPT6H抗体Applications

Tested Applications: ELISA, WB, IP
Specificity Reaction: Human,Mouse,Rat; Other species are not tested.Please decide the specificity by homology
Positive WB detected in HeLa cells, HEK-293 cells, Jurkat cells
Positive IP detected in HEK-293 cells
Recommended dilution WB : 1:500-1:5000
IP : 1:500-1:5000
 SUPT6H抗体Application key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence
Images
Prev1NextView more validation data
  • 23073-1-AP;HeLa cellHeLa cells were subjected to SDS PAGE followed by western blot with 23073-1-AP(SUPT6H antibody) at dilution of 1:1000
  • 23073-1-AP;HEK-293 cellsIP Result of anti-SUPT6H (IP:23073-1-AP, 4ug; Detection:23073-1-AP 1:1000) with HEK-293 cells lysate 1200ug.
Product Information
Source: Rabbit Purify: Antigen affinity purification
IsoType: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles.
Immunogen Information SUPT6H抗体
Immunogen: SUPT6H fusion protein ag19426 Full Name: Suppressor of Ty 6 homolog (S. cerevisiae)
Caculated Molecular
Weight:		 1726aa,199 kDa Observed Molecular 
Weight:		 230 kDa
GenbankNo BC136524 GeneID: 6830
Symbol SUPT6H Synonyms Emb 5, hSPT6, KIAA0162, SPT6, SPT6H, SUPT6H, Tat cotransactivator 2 protein, Tat CT2 protein
Background

SUPT6H (suppressor of Ty6 homolog), also known as SPT6, SPT6H, Tat-CT2 (Tat-cotransactivator 2 protein) or emb-5 in C. elegans, is a 1,726 amino acid protein that is highly conserved from yeast to humans. Expressed ubiquitously, SUPT6H localizes to the nucleus and contains one SH2 domain and one S1 domain. SUPT6H participates in both DRB (5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole)-mediated transcriptional inhibition as well as the enhancement of transcriptional elongation by the RNA polymerase II (Pol II). SUPT6H interacts with the nuclear proteins SPT4 and SPT5, which comprise the DSIF (DRB-sensitivity-inducing factor) complex that binds RNA polymerase II, and directly regulates elongation. Via its C-terminus, SUPT6H can also interact with Histone H3. Due to alternative splicing events, three isoforms exist for SUPT6H. This antibody specifically recognizes the 230kd phosphorylated SUPT6H protein. SUPT6H抗体

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