FITC标记的线粒体核糖体蛋白S18C抗体
产品名称: FITC标记的线粒体核糖体蛋白S18C抗体
英文名称: Anti-MRPS18C/FITC
产品编号: HZ-17817R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-MRPS18C/FITC Conjugated antibody
FITC标记的线粒体核糖体蛋白S18C抗体
英文名称 | Anti-MRPS18C/FITC |
中文名称 | FITC标记的线粒体核糖体蛋白S18C抗体 |
别 名 | 28S ribosomal protein S18 1, mitochondrial; 28S ribosomal protein S18-1; 28S ribosomal protein S18c; 28S ribosomal protein S18c mitochondrial; CGI-134; mitochondrial; Mitochondrial ribosomal protein S18 1; Mitochondrial ribosomal protein S18C; MRP-S18-1; MRP-S18-c; MRPS18 1; Mrps18-c; Mrps18c; RT18C_HUMAN; S18mt-c. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 转录调节因子 细胞类型标志物 线粒体 表观遗传学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Pig, Cow, Horse, Sheep, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 16kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human MRPS18C |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 8p, 12p, 15q, and 22q. [provided by RefSeq, Jul 2008] Subunit: Component of the mitochondrial ribosome small subunit Subcellular Location: Mitochondrion. Similarity: Belongs to the ribosomal protein S18P family. Database links: Entrez Gene: 51023 Human Entrez Gene: 68735 Mouse Entrez Gene: 289469 Rat Omim: 611983 Human SwissProt: Q9Y3D5 Human SwissProt: Q8R2L5 Mouse Unigene: 334772 Human Unigene: 436161 Human Unigene: 25585 Mouse Unigene: 105741 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
哺乳动物线粒体核糖体蛋白由核基因编码,并有助于线粒体内的蛋白质合成。线粒体核糖体(线粒体核糖体)由一个小的28 S亚基和一个大的39 S亚基组成。与原核核糖体相比,它们具有75%的蛋白-rRNA组成,其中该比率是相反的。哺乳动物线粒体核糖体和原核核糖体的另一个区别是后者含有5S rRNA。在不同物种中,包含有丝分裂体的蛋白质在序列上有很大差异,有时在生化性质上有很大差异,这妨碍了通过序列同源性很容易识别。该基因编码属于核糖体蛋白S18P家族的一个28 S亚基蛋白。编码的蛋白质是与细菌S18蛋白具有显著序列相似性的三种蛋白质之一。三种人线粒体S18蛋白的初级序列与原核S18蛋白之间没有更密切的关系。与此基因相对应的假基因在染色体8p、12p、15q和22q上发现。〔RefSeq,Jul 2008〕