FITC标记的单纯疱疹病毒1型DNA聚合酶催化亚单位抗体
产品名称： FITC标记的单纯疱疹病毒1型DNA聚合酶催化亚单位抗体
英文名称： Anti-HHV11 DNA polymerase catalytic subunit/FITC
产品编号： HZ-10489R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-HHV11 DNA polymerase catalytic subunit/FITC Conjugated antibody
FITC标记的单纯疱疹病毒1型DNA聚合酶催化亚单位抗体
| 英文名称 | Anti-HHV11 DNA polymerase catalytic subunit/FITC |
| 中文名称 | FITC标记的单纯疱疹病毒1型DNA聚合酶催化亚单位抗体 |
| 别 名 | DPOL_HHV11; DNA polymerase catalytic subunit; UL30; HHV1gp046. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 微生物学 细菌及病毒 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Herpes simplex virus (type 1 / strain 17) |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 136kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human HHV11 DNA polymerase catalytic subunit |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | Function: Replicates viral genomic DNA. The replication complex is composed of six viral proteins: the DNA polymerase, processivity factor, primase, primase-associated factor, helicase, and ssDNA-binding protein. Additionally, the polymerase contains an intrinsic ribonuclease H (RNase H) activity that specifically degrades RNA/DNA heteroduplexes or duplex DNA substrates in the 5' to 3' direction. Therefore, it can catalyze the excision of the RNA primers that initiate the synthesis of Okazaki fragments at a replication fork during viral DNA replication. Subunit: Forms a complex with the ssDNA-binding protein UL29, the DNA polymerase processivity factor, and the alkaline exonuclease. Interacts with the putative helicase-primase complex subunit UL8; this interaction may coordinate leading and lagging strand DNA synthesis at the replication fork (By similarity). Subcellular Location: Host nucleus (Potential). Note=The protein is present at discrete sites in nuclei, called replication compartments where viral DNA replication occurs (By similarity). Similarity: Belongs to the DNA polymerase type-B family. Database links:
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
复制病毒基因组DNA。复制复合物由六种病毒蛋白组成：DNA聚合酶、加工因子、引物、引物相关因子、螺旋酶和ssDNA结合蛋白。此外，该聚合酶含有内在核糖核酸酶H（RNase H）活性，该活性在5’至3’方向上特异性降解RNA/DNA异双链或双链DNA底物。因此，它可以催化RNA引物的切除，在病毒DNA复制期间在复制叉上启动冈崎片段的合成。