SLC12A6 polyclonal antibody
产品名称： SLC12A6 polyclonal antibody
英文名称： SLC12A6 polyclonal antibody
产品编号： PAB7377
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of SLC12A6.
- Immunogen:
- A synthetic peptide corresponding to human SLC12A6.
- Sequence:
- SRHIDVCSKTKE
- Host:
- Goat
- Theoretical MW (kDa):
- 128, 122, 121, 127,
- Reactivity:
- Human
- Specificity:
- This antibody is expected to recognize all 6 reported isofoms (NP_598408.1, NP_005126.1, NP_0010.35959.1, NP_0010.35960.1, NP_0010.35961.1, NP_0010.35962.1, ).
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:16000)
Western blot (0.1-0.3 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2-4 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Homooligomeric and heterooligomeric associations between K+-Cl- cotransporter isoforms and between K+-Cl- and Na+-K+-Cl- cotransporters.
Simard CF, Bergeron MJ, Frenette-Cotton R, Carpentier GA, Pelchat ME, Caron L, Isenring P.J Biol Chem. 2007 Jun 22;282(25):18083-93. Epub 2007 Apr 26.
- Applications
- Western Blot (Tissue lysate)
- SLC12A6 polyclonal antibody (Cat # PAB7377) (0.1 ug/mL) staining of human heart lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
- Entrez GeneID:
- 9990
- Protein Accession#:
- NP_0010.35959.1;NP_0010.35960.1;NP_0010.35961.1;NP_0010.35962.1;NP_005126.1;NP_598408.1
- Gene Name:
- SLC12A6
- Gene Alias:
- ACCPN,DKFZp434D2135,KCC3,KCC3A,KCC3B
- Gene Description:
- solute carrier family 12 (potassium/chloride transporters), member 6
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy. [provided by RefSeq
- Other Designations:
- potassium chloride cotransporter 3,potassium chloride cotransporter KCC3a-S3,solute carrier family 12, member 6