FITC标记的多能发育相关基因2抗体
产品名称： FITC标记的多能发育相关基因2抗体
英文名称： Anti-DPPA2/FITC
产品编号： HZ-
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-DPPA2/FITC Conjugated antibody
FITC标记的多能发育相关基因2抗体
| 英文名称 | Anti-DPPA2/FITC |
| 中文名称 | FITC标记的多能发育相关基因2抗体 |
| 别 名 | Developmental Pluripotency Associated 2; developmental pluripotency associated gene2; PESCRG1; Pluripotent embryonic stem cell related protein 1; cancer/testis antigen 100; CT100; developmental pluripotency-associated gene 2; developmental pluripotency-associated protein 2; ECAT15-2; embryonic stem cell (ESC) associated transcript 15-2; PESCRG1; Pluripotent embryonic stem cell related protein 1; Pluripotent embryonic stem cell-related gene 1; Pluripotent embryonic stem cell-related gene 1 protein . |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 发育生物学 神经生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 34kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DPPA2 (211-301aa) |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: SCRG1 (scrapie-responsive protein 1) is a 98 amino acid secreted protein that belongs to the SCRG1 family. The SCRG1 protein contains a 20-amino acid signal peptide, and is expressed abundantly in the central nervous system of human adult, but not at all in fetal brain. The protein is targeted to the Golgi apparatus and large dense-core vesicles/secretory granules in neurons. High levels of SCRG1 transcripts are also observed in testis and aorta. SCRG1 is associated with neurodegenerative changes observed in transmissible spongiform encephalopathies. It may play a role in host response to prion-associated infections. The SCRG1 protein may be partly included in the membrane or secreted by the cells due to its hydrophobic N-terminus. The human and mouse SCRG1 proteins share 83% sequence identity. The SCRG1 gene is conserved in chimpanzee, cow, mouse, rat and chicken, and maps to human chromosome 4q34.1. Function: Dppa2 is a SAP domain protein expressed only in pluripotent cells and the developing germ line. Subcellular Location: Secreted. Tissue Specificity: Expressed abundantly in the central nervous system of adult, but not at all in fetal brain. High levels of SCRG1 transcripts are also observed in testis and aorta. Similarity: Belongs to the SCRG1 family. Database links: Entrez Gene: 151871 Human Entrez Gene: 73703 Mouse Omim: 614445 Human SwissProt: Q7Z7J5 Human SwissProt: Q9CWH0 Mouse Unigene: 351113 Human Unigene: 27857 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
SCRG1（痒病应答蛋白1）是属于SCRG1家族的98氨基酸分泌蛋白。SCRG1蛋白含有20个氨基酸的信号肽，在中枢神经系统中表达丰富，而在胎儿脑中则完全不表达。该蛋白靶向高尔基体和大致密核心囊泡/分泌颗粒在神经元中。在睾丸和主动脉中也观察到高水平的SCRG1转录本。SCRG1与可传播海绵状脑病中观察到的神经退行性改变有关。它可能在朊病毒相关感染的宿主反应中起作用。SCRG1蛋白可部分地包含在膜中，或由于其疏水性的N-末端而被细胞分泌。人和小鼠SCRG1蛋白共有83%个序列同源性。SCRG1基因在黑猩猩、牛、小鼠、大鼠和鸡中是保守的，并映射到人类染色体4q34.1。