FITC标记的脑特异性血管生成抑制蛋白1抗体
产品名称： FITC标记的脑特异性血管生成抑制蛋白1抗体
英文名称： Anti-BAI1/FITC
产品编号： HZ-7513R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749 点击查看
- 传真 : 点击查看
- 邮箱 : www.shzbio.net
- 二维码 : 点击查看
Rabbit Anti-BAI1/FITC Conjugated antibody
FITC标记的脑特异性血管生成抑制蛋白1抗体
| 英文名称 | Anti-BAI1/FITC |
| 中文名称 | FITC标记的脑特异性血管生成抑制蛋白1抗体 |
| 别 名 | BAI 1; BAI-1; Brain specific angiogenesis inhibitor 1; mKIAA4089; KIAA4089; R75078; B830018M07Rik; BAI1_HUMAN |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 心血管 细胞生物 免疫学 血管内皮细胞 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Cow, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 170kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human BAI1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: BAI 1 protein is likely to be a potent inhibitor of angiogenesis in brain and may play a significant role as a mediator of the p53 signal in suppression of glioblastoma. It may function in cell adhesion and signal transduction in the brain. Reduced or no expression is observed in some glioblastoma cell lines and cancer tissues. Function: Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Likely to be a potent inhibitor of angiogenesis in brain and may play a significant role as a mediator of the p53 signal in suppression of glioblastoma. May function in cell adhesion and signal transduction in the brain. Subunit: Interacts with ELMO1 and DOCK1. When bound to ELMO1 and DOCK1, it may act as a module to promote the engulfment. Interacts with MAGI1, MAGI3, BAIAP2 and PHYHIP. Subcellular Location: Cell membrane; Multi-pass membrane protein. Note=Likely to be concentrated at cell-cell adhesion sites. Tissue Specificity: Specifically expressed in brain. Reduced or no expression is observed in some glioblastoma cell lines and cancer tissues. No expression in astrocytes. Post-translational modifications: The endogenous protein is proteolytically cleaved into 2 subunits, an extracellular subunit and a seven-transmembrane subunit. Similarity: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. Contains 1 GPS domain. Contains 5 TSP type-1 domains. Database links: Entrez Gene: 524070 Cow Entrez Gene: 575 Human Entrez Gene: 107831 Mouse Entrez Gene: 362931 Rat Omim: 602682 Human SwissProt: O14514 Human SwissProt: Q3UHD1 Mouse Unigene: 194654 Human Unigene: 43133 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application |
白细胞介素1蛋白可能是脑血管生成的有力抑制剂，在抑制胶质母细胞瘤的p53信号中起重要作用。它可能在大脑中的细胞粘附和信号转导中起作用。在某些胶质母细胞瘤细胞系和癌组织中观察到表达减少或不表达。