CBFA2T2抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
CBFA2T2抗体

CBFA2T2抗体

商家询价

产品名称： CBFA2T2抗体

英文名称： CBFA2T2Antibody

产品编号： XY11336-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 CBFA2T2抗体

Applications
In-house applications ELISA, WB, IHC     Application not tested? Please see our Guarantee.
Species specificity Human, mouse, rat; other species not tested.
Images
Prev1NextView more validation data
  • 11336-1-AP;HEK-293 cellHEK-293 cells were subjected to SDS PAGE followed by western blot with 11336-1-AP(CBFA2T2 antibody) at dilution of 1:300
  • 11336-1-AP;GliomasImmunohistochemical of paraffin-embedded human gliomas using 11336-1-AP(CBFA2T2 antibody) at dilution of 1:50 (under 10x lens)
Positive WB detected in HEK-293 cells, mouse testis tissue, PC-3 cells
Positive IHC detected in Human gliomas
Recommended dilution WB : 1:200-1:2000
IHC : 1:20-1:200
 CBFA2T2抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen CBFA2T2 fusion protein ag1880 Full name Core-binding factor, runt domain, alpha subunit 2; translocated to, 2
Calculated molecular
weight		 604aa,67 kDa Observed molecular 
weight		 85kd
GenBank accession 
number		 BC015066 Gene ID (NCBI) 9139
Gene symbol CBFA2T2 Synonyms CBFA2T2, Protein CBFA2T2, p85, ZMYND3, MTG8 like protein
Background CBFA2T2抗体

Core-binding factor, runt domain, alpha subunit 2, translocated to 2(CBFA2T2) belongs to a family of ubiquitously expressed transcriptional repressors that interact with transcription factors bound to promoters of target genes and with histone deacetylases (HDACs) critical for enforcement of repressor function.CBFA2T2, also named as MTGR1 or EHT, is an 85-kDa phosphoprotein. It can bind AML1-MTG8 fusion protein in acute myeloid leukemia. The binding leads to an enhancement of cell proliferation mediated in a murine myeloid model. CBFA2T2抗体

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